Radioisotope scanning in auxiliary liver transplantation.

The same general techniques were used in both the canine and human studies. Intravenously administered rose bengal 1131 was administered to dogs in a dose of 50 microcuries and to patients in a dose of 150 microcuries; scans were obtained at 5 minutes. In the canine experiments employing gold, 50 microcuries of Aulg8 were used with scanning at 15 minutes; in 2 adult human beings 200 microcuries were administered and scans obtained at 45 minutes. In a third patient, a 6.4 kilogram child, 11 microcuries of Aulg8 were administered and the scan started immediately. Scans were obtained with a 5 by 2 inch crystal and a 5 inch broad focus collimator. The spectrophotometer was set at 0.345 to 0.395 million electron volts for the 1131 and 0.355 to 0.455 million electron volts for the Aulg8. Scan speed was 90 cubic centimeters per minute, with a line spacing of 0.45 cubic centimeter. Density was adjusted according to the counts per minute. Background cutoff was 15 per cent plus or minus 5 per cent,